Question 1

What is tDCS and how does it help with treatment-resistant depression?

Accepted Answer

Transcranial direct current stimulation (tDCS) is a non-invasive neuromodulation technique that applies low-intensity electrical currents over the left dorsolateral prefrontal cortex (DLPFC). In treatment-resistant depression, this area shows hypoactivity. tDCS increases cortical excitability, rebalancing brain activity without medications. At GNeuro, we use the Sooma DUO protocol (clinical) and Flow (home-based) for comprehensive treatment.

Question 2

How many tDCS sessions are needed to see depression improvement?

Accepted Answer

The standard tDCS protocol for treatment-resistant depression consists of 15-20 sessions in the acute phase (5 sessions/week for 3-4 weeks). Initial effects typically appear by week 2. Afterward, a home maintenance program using the Flow headset is recommended (2-3 sessions/week). Studies show response rates of 40-60% in treatment-resistant depression, significantly superior to placebo.

Question 3

Is home-based tDCS safe for depression?

Accepted Answer

Yes, home-based tDCS is safe when using a certified device like the Flow headset, which is approved as a medical device. Side effects are mild and transitory (slight tingling at the stimulation site). At GNeuro, home programs always begin after in-person clinical evaluation and continue under biweekly telemedical supervision to adjust parameters based on patient progress.